Process Development Senior Scientist

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Let’s do this. Let’s change the world. In this vital role you will be responsible for the invention, development, characterization, and implementation of synthetic drug substance manufacturing processes and technologies to advance Amgen's exciting small molecule and hybrid portfolio. The Senior Scientist role will include supporting the development of efficient and sustainable manufacturing processes to prepare peptides, oligonucleotides, and/or antibody drug conjugates, driving technology innovation to support bioconjugation, and providing technical expertise towards manufacturing and commercialization.

Responsibilities:

• Work with a diverse team of synthetic chemists, chemical engineers and analytical chemists to develop sustainable and cost-effective processes for synthetic peptide, oligonucleotide, and/or antibody drug conjugate manufacturing
• Drive technology innovation in the synthesis, purification, and characterization of bioconjugates
• Support cGMP manufacturing and technology transfer to large-scale production facilities
• Develop strategies to ensure process performance through process understanding, modeling and characterization
• Guide successful completion of project deliverables and ensure timelines are met
• Work cross-functionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of peptide, oligonucleotide, and antibody drug conjugate manufacturing
• Coach and provide career and scientific / technical advice to colleagues within the organization
• Interface with Research / Discovery teams to advance programs into Process Development and towards clinical development milestones.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

Or

Master’s degree and 3 years of Chemistry, Biochemistry, or Chemical Biology experience

Or

Bachelor’s degree and 5 years of Chemistry, Biochemistry, or Chemical Biology experience

Preferred Qualifications:

• Extensive hands-on expertise in the synthesis and purification of peptides, oligonucleotides, and/or antibody drug conjugates and experience with bioconjugation techniques
• Proficiency in analytical characterization techniques such as Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid Chromatography–Mass Spectrometry (LC-MS), Ion-Exchange (IEX), and Reversed Phase (RP)-HPLC.
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
• People-centered leadership skills in building strong teams through mutual trust and respect and exhibits Amgen leadership attributes of inspire, accelerate, integrate, and adapt
• Proven track record of publications, patents and presentations

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.