Principal Software Development Engineer

Join our team at Amgen Capability Center Portugal, the #1 company in Best Workplaces™ (201–500 employees category) by the Great Place to Work Institute. With over 400 talented individuals from more than 40 nationalities, our Lisbon center thrives at the intersection of innovation, excellence, and inspiration. This is your opportunity to explore the future of healthcare through technology and digital innovation, supporting our mission To Serve Patients. 

PRINCIPAL SOFTWARE DEVELOPMENT ENGINEER

At Amgen, Technology isn’t just a support function—it’s a catalyst for discovery, transformation, and real-world impact. Here, your ideas fuel innovation that improves and saves lives of patients in dire need of our medicines. Are you ready to do meaningful work that matters?

LIVE
What you will do

As a Principal Software Development Engineer, you’ll work at the intersection of science, data, and innovation. You’ll collaborate with world-class experts across domains to build high-impact digital solutions that accelerate research, streamline operations, and empower better patient outcomes. 

In this pivotal leadership role, you will lead the development and delivery of innovative software solutions and play a pivotal role in shaping our technology strategy and mentoring a team of talented engineers.  
Let’s do this. Let’s change the world. In this vital role you will:

• Possesses strong rapid prototyping skills and can quickly translate concepts into working code 

• Provide technical guidance and mentorship to the development team. 

• Take ownership of complex software projects from conception to deployment. Manage software delivery scope, risk, and timeline 

• Contribute to both front-end and back-end development using cloud technology. 

• Develop innovative solution using latest technologies 

• Define and implement robust software architectures on the cloud, AWS preferred 

• Lead and motivate a team of engineers to deliver high-quality results. 

• Conduct code reviews to ensure code quality and adherence to best practices.  

• Create and maintain documentation on software architecture, design, deployment, disaster recovery, and operations. 

• Identify and resolve technical challenges effectively. 

• Stay updated with the latest trends and advancements 

• Work closely with product team, business team, and other stakeholders. 

WIN
What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The tech professional we seek is a creative problem-solver and a team player with these qualifications:

• Bachelor’s or Master’s degree in Computer Science, and engineering preferred, other Engineering field is considered. 

• Cloud Computing certificate preferred.

• Fluency in English.

• Strong verbal and written communication skills 

Must-Have Skills: 

• Hands on experience with various cloud services, understand pros and cons of various cloud service in well architected cloud design principles 

• Hands on experience with Full Stack software development.

• Proficient in programming language Python(preferred), JavaScript, SQL/NoSQL.  

• Proven ability to lead and mentor software development teams 

• Strong problem solving, analytical skills; Ability to learn quickly; Excellent communication and interpersonal skills 

Good-to-Have Skills: 

• Experienced with API integration, serverless, microservices architecture. 

• Experience in SQL/NOSQL database, vector database for large language models 

• Experience with popular large language models 

• Experience with Langchain or llamaIndex framework for language models 

• Experience with prompt engineering, model fine tuning 

• Experience with Web site development, understand of web site localization processes, which involve adapting content to fit cultural and linguistic contexts. 

• Experience with DevOps CICD build and deployment pipeline 

• Experience with design patterns, data structures, test-driven development. 

• Knowledge of different techniques for text analysis and sentiment analysis 

THRIVE
What you can expect of us

As we work to develop treatments that take care of others, we also care deeply for our teammates’ well-being and growth.

• Work That Matters – Build tech that accelerates scientific breakthroughs and helps patients worldwide.

• Modern Tech Stack – Cloud-first, automation-focused, AI-powered.

• Global Scale, Agile Mindset – Collaborate across continents while working in nimble, high-impact teams.

• Continuous Learning – Access to certifications, trainings, mentorship, and career mobility.

• Amgen Total Rewards Plan – Comprehensive benefits in healthcare, finance, and well-being.

• Flexibility – Hybrid work model with time split between our Lisbon office and remote work.

APPLY NOW
Objects in your future are closer than they appear. Join us.
CAREERS.AMGEN.COM

EQUAL OPPORTUNITY STATEMENT
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation