Process Development Sr Scientist

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Let’s do this. Let’s change the world! In this vital role, you will lead mass spectrometry-based analytical development, driving innovation in protein and macromolecule characterization to support drug substance and drug product development. You will apply sophisticated LC-MS techniques, data analysis, and method development to solve complex analytical challenges, collaborate cross-functionally, and contribute to the advancement of ground breaking biopharmaceuticals.

Specific responsibilities include but are not limited to:

• Design and execute mass spectrometry experiments to characterize proteins, monoclonal antibodies, and macromolecules using advanced analytical techniques.
• Lead and drive Liquid Chromatography-Mass Spectrometry (LC-MS) method development for various sample matrices, including Drug Substance (DS) and Drug Product (DP).
• Establish acceptance criteria, conduct technical data reviews, analyze and interpret mass spectrometry data, and generate comprehensive technical reports.
• Train and mentor Analytical Scientists in mass spectrometry techniques, ensuring proficiency in experimental design, data analysis, and instrument operation.
• Investigate and characterize unknown peaks in Drug Substance, Drug Product, and in-process samples, applying advanced analytical problem-solving skills.
• Perform mass spectrometry data analysis and interpretation, generating detailed reports and technical summaries to support decision-making.
• Collaborate cross-functionally with scientific and technical teams to design experiments, interpret results, and provide mass spectrometry expertise in analytical development.
• Experience in gas chromatography is a plus, providing additional expertise in analytical separation techniques.
  

What we expect of you

We are all different! Yet, we all use our unique contributions to serve patients. The Process Development Senior Scientist professional we seek is an individual contributor with these qualifications.

Basic Qualifications:

Doctorate degree

Or

Master’s degree and 3 years of Scientific experience

Or

Bachelor’s degree and 5 years of Scientific experience

Preferred Qualifications:

• Hands-on experience with mass spectrometry (MS), including high-resolution mass spectrometry (HRMS) and data processing using various software.
• Strong understanding of mass spectrometry principles, including MS and MS/MS techniques, ionization methodologies for large and small molecules, and analytical method development.
• Proven expertise in the operation, calibration, maintenance, and troubleshooting of MS instruments, with the ability to interpret complex analytical data.
• Advanced problem-solving skills, with the ability to analyze raw data and apply scientific reasoning to resolve analytical challenges.
• Proficiency in liquid chromatography-mass spectrometry (LC-MS) and high-performance liquid chromatography (HPLC), including method development and optimization.
• Experience with chromatography data systems (CDS), such as Chromeleon, Atlas, Empower, or similar platforms for data acquisition and analysis.
• Bilingual proficiency in English and Spanish, with strong verbal and written communication skills for technical reporting and collaboration.
  

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and an annual site shutdown
• Flexible work models, including remote work arrangements, where possible
  

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

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As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.