Senior Program Manager, Direct-to-Patient – MariTide

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Amgen is now preparing to enter the obesity market. Its lead candidate, MariTide, is in Phase 3 development and has shown competitive weight-loss efficacy, a strong safety profile, and a convenient dosing interval. The Phase 3 MARITIME program is studying MariTide in obesity and overweight and in obesity-related conditions—including type 2 diabetes, heart failure, obstructive sleep apnea, and atherosclerotic cardiovascular disease—alongside a broader pipeline of oral and injectable, incretin and non-incretin approaches. To move with speed, Amgen has stood up a dedicated organization focused on obesity and related conditions. Headquartered in Thousand Oaks, California, Amgen employs roughly 31,500 people worldwide and reported $36.8 billion in total revenue in 2025.

Senior Program Manager, Direct-to-Patient – MariTide

This role will support the U.S. launch of MariTide, Amgen is building a Direct-to-Patient (DTP) channel that operates alongside traditional access pathways. The model combines digital intake, telehealth-enabled care, and end-to-end fulfillment into a single, integrated experience that routes patients across cash-pay and reimbursed options based on their needs and coverage.

Reporting to the Executive Director, US Direct-to-Patient Lead, the Senior Program Manager drives the execution and launch readiness of this model. Where the Executive Director sets the strategy and operating model, the Senior Program Manager turns that direction into an integrated, well-governed program:  Orchestrating the cross-functional build, owning the plan and critical path, and ensuring every workstream and partner is ready for launch. This is a high-visibility role at the center of a fast-moving, highly regulated program where execution directly affects patient conversion, adherence, and long-term franchise growth.

Key Activities and Accountabilities

• Program Management & Launch Readiness

  • Build and own the integrated DTP launch plan and roadmap spanning intake, telehealth, prescribing, fulfillment, billing, and patient support, with clear milestones, owners, and critical path

  • Manage cross-workstream dependencies, timelines, and resourcing; surface trade-offs early and keep the program tracking to committed launch dates

  • Run launch-readiness and Go/No-Go processes, including readiness criteria, checklists, and end-to-end dry runs

  • Lead risk, issue, and action management (RAID), driving timely escalation and resolution

• Cross-Functional Orchestration

  • Coordinate execution across Marketing, Value & Access, Medical, Regulatory, Legal, Tax, Operations, and Commercial Data & Analytics (CD&A)

  • Drive decisions through established governance forums; capture and track decisions, actions, and follow-through to closure

  • Produce clear status reporting and executive updates that give leadership a reliable view of progress, risk, and readiness

• Partner & Vendor Program Management

  • Coordinate onboarding, integration, and testing of telehealth, fulfillment, pharmacy, and platform partners in support of the partner strategy set by the Executive Director

  • Plan and manage UAT and end-to-end testing across the patient journey; track defects to closure

  • Monitor partner readiness and SLA commitments ahead of launch and flag gaps with enough runway to act

• Operating Cadence & Governance

  • Establish and run the program operating rhythm, including steering committees, workstream syncs, and reporting cadence

  • Maintain the single source of truth for plan, status, decisions, and risks

  • Develop pre-reads and materials that drive efficient, decision-oriented meetings

• Performance Tracking & Continuous Improvement

  • Partner with CD&A to stand up dashboards and KPIs for conversion, adherence, SLA performance, and channel effectiveness

  • Track performance against plan and support structured testing and optimization

  • Lead retrospectives and capture lessons learned to strengthen readiness for future indications and launch waves

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a manager with these qualifications.

Basic Qualifications

• Doctorate degree and 2 years of program/project management, commercial, digital health, or operations experience OR

• Master's degree and 4 years of program/project management, commercial, digital health, or operations experience OR

• Bachelor’s degree and 6 years of program/project management, commercial, digital health, or operations experience OR

• Associate’s degree and 10 years of program/project management, commercial, digital health, or operations experience OR

• High school diploma / GED and 12 years of program/project management, commercial, digital health, or operations experience

Preferred Qualifications

• Program or project management experience in digital health, pharma/biotech commercialization, telehealth, or consumer health

• Proven skill navigating matrixed organizational structures, moving with speed and accountability without burning bridges or circumventing necessary steps

• Track record managing complex, multi-stakeholder launches under compressed timelines, including Go/No-Go decision frameworks

• Experience coordinating internal and external partners and vendors (IT, marketing, fulfillment, telehealth, pharmacy, platform, and others), including integration testing, UAT, and SLA tracking

• Comfort operating in highly regulated environments, partnering closely with Legal, Regulatory, Compliance, and Government Pricing

• Technical fluency to partner with product and engineering on system integration, API integrations, data flows, and performance dashboards

• Proficiency with program/project management tools and methods (e.g., Smartsheet, Jira, MS Project; Agile and waterfall); CSM, PMP, or equivalent certification a plus

• Strong communication, stakeholder management, and executive reporting skills

• Data-driven mindset with comfort navigating ambiguity and competing priorities in a high-visibility launch environment

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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