Scientific Director

The Translational Safety & Risk Sciences (TSRS) function at Amgen is seeking a Scientific Director to serve as a Project Toxicologist and a Subject Matter Expert, reporting to the Senior Director Head Therapeutic Area Strategy Leaders and Business Development Liaisons.

You will develop and implement a fit-for-purpose nonclinical safety strategy based on a strong scientific foundation, flexibly evolve the strategy in response to team goals and emerging data and lead multidisciplinary TSRS teams. As a project team representative (PTR), you will partner with project teams developing therapeutics leveraging a variety of modalities (including biotherapeutics, small molecules and RNA therapies) to treat diseases in inflammation, oncology and/or cardiometabolic diseases, including obesity and rare diseases. There is potential for opportunities with broader Inflammation and/or Oncology Therapeutic Area responsibilities and to conduct scientific due diligence for business development opportunities in oncology and CMD therapeutic areas.  PTRs are encouraged to develop subject matter expertise related to a specific modality, therapeutic area, or safety concern.

The successful candidate will have:

• A proven sustained track record of scientific leadership in drug development (including IND/CTA filings) as well as in nonclinical development with a strong understanding of cross-functional needs and the ability to develop integrated plans to enable successful development of a therapeutic.
• Experience with matrix management and demonstrated effective mentoring skills.
• Presented nonclinical safety issues at national and international regulatory meetings and participate in external industry initiatives to improve drug safety assessment paradigms

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is innovative with these qualifications.

Basic Qualifications

• Doctorate degree in Toxicology or a related scientific field, and 4 years of experience OR
• Master’s degree and 7 years of experience OR
• Bachelor’s degree and 9 years of experience
• Excellent and professional communicator; proven ability to influence a broad spectrum of partners toward achieving business goals

Preferred Qualifications

• A minimum of 10 years of drug development experience, at all stages of development including late-stage assets and interactions with global regulatory agencies for IND/CTA and NDA/BLA filings
• Expertise in the field of immunology, either through immune-toxicology, immune-oncology or immunology related drug-target support.
• End-to-end small and large molecule safety assessment experience across multiple therapeutic areas and modalities potentially including antibody drug conjugates and T-cell engagers
• External visibility as a toxicology expert as demonstrated by a strong external presentation and publication record and leadership of external collaborative groups
• Comfortable operating as a cross-functional and inter-functional thought partner on multi-disciplinary teams across R&D functions
• Experience supporting business development efforts in the conduct of due diligence evaluations as translational safety team member
• Experienced scientific leader with direct or matrixed management experience
• Diplomate of the American Board of Toxicology

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.