Program Management Lead – Content Transformation

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Program Management Lead – Content Transformation

What you will do

Let’s do this. Let’s change the world. The PMO Lead - Content Transformation will provide program-level planning, integration, and governance across Global Commercial Capabilities (GCC)’s Content Transformation initiatives, including Data Privacy &Measurement and Content Production & Deployment. This leader will lead a group of related projects as a cohesive program to realize outcomes and benefits not attainable through individual project management alone. They will help to oversee the successful delivery of new enterprise capabilities and operational model, ensuring alignment with organizational strategy, business priorities, and transformation goals.

Acting as the connective link across business, data, and technology functions, the PMO Lead will establish consistent program standards for planning, execution, and performance measurement. Serving as a trusted advisor to senior sponsors and cross-functional partners, this leader will develop clarity, accountability, and decision-making with speed, driving measurable impact and sustained success across all content transformation workstreams.

Governance and Senior Leadership Support

• Lead and constantly refine integrated governance across transformation to align priorities with Amgen’s enterprise strategy.
• Provide senior leadership with weekly status, structured insight into program health and business value delivery, interdependencies, and risk.
• Act as a strategic partner to executive sponsors—translating strategic direction into actionable plans and measurable outcomes.
• Drive decision-making cadence and alignment by facilitating structured governance forums, including the Cross-Functional Executive Committee and Transformation Steering Committees.

Planning and Program Oversight

• Oversee cross-functional delivery across multiple transformation workstreams, ensuring execution rigor, achievement tracking, and dependency management.
• Facilitate cross-synchronization sessions with business and tech leads, and leadership readouts to ensure continuity and connection across initiatives.
• Maintain comprehensive program documentation, RACI matrices, and decision logs in alignment with program management frameworks.
• Partner with leads to anticipate resource needs, surface delivery risks, and recommend mitigations.
• Lead quarterly MVP planning sessions across workstreams to provide one comprehensive timeline and roadmap and ensure all relevant partners are informed of outputs.

Financial & Resource Management

• Lead financial governance at program-level, ensuring clear insight into budget utilization, vendor performance, and forecast accuracy.
• Drive submission preparation and documentation for formal financial approval requests, ensuring accuracy, alignment with business case, and timely delivery. Partner with Finance and cross-functional leads to develop materials and ensure senior leadership is fully briefed and prepared to represent program priorities and funding needs at financial meetings.
• Track program budget burn and resource allocation, calling out potential constraints to executive sponsors quickly.

Performance Measurement & Reporting

• Establish a standardized reporting framework that integrates KPIs, metrics, and performance dashboards to track transformation progress and outcomes at program-level.
• Collaborate with business leads to define measurable success indicators tied to adoption, speed-to-market, savings, and engagement quality, rolling them up to program-level.
• Translate operational data into insights for senior leadership to inform prioritization, investment, and change management decisions.
• Provide Portfolio Management Office with metrics and updates for reporting.
• Ensure program-level KPIs are consistent and delivered on time for QBRs.

Change Management & Communications

• Develop and implement program-level change management strategies which incorporate change management needs of all workstreams – securing senior leadership consensus, supporting adoption of new capabilities, processes, and governance practices.
• Partner with Cross-Workstream Communications Team to align messaging, timing, and readiness activities across partner groups.
• Craft concise executive narratives to communicate program outcomes, breakthroughs, and decisions across the global enterprise.

Operational Excellence & Risk Management

• Maintain a centralized risk and issue register with defined escalation pathways and accountability owners.
• Conduct quarterly retrospectives and continuous improvement sessions to refine PMO operations and decision frameworks.
• Ensure consistent application of program management standards across planning, execution, and governance documentation.
• Promote a culture of operational rigor, clarity, and proactive problem-solving across transformation teams.

This role is central to Amgen’s ability to deliver transformation with structure, clarity, and measurable value. If you are passionate about enabling enterprise change, building scalable governance systems, and influencing strategic outcomes, we invite you to join us in reimagining how Amgen leads global transformation.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a strategic partner with these qualifications.

Basic Qualifications:

Doctorate degree and 3 years of experience in program or portfolio management, preferably within enterprise transformation or PMO leadership roles

OR

Master’s degree and 5 years of experience in program or portfolio management, preferably within enterprise transformation or PMO leadership roles

OR

Bachelor’s degree and 7 years of experience in program or portfolio management, preferably within enterprise transformation or PMO leadership roles

OR

Associate’s degree and 12 years of experience in program or portfolio management, preferably within enterprise transformation or PMO leadership roles

OR

High school diploma / GED and 14 years of experience in program or portfolio management, preferably within enterprise transformation or PMO leadership roles

Preferred Qualifications:

• Master’s degree in Business, Technology Management, or Organizational Leadership.
• PMP, PgMP, or PMO-CP certification.
• Experience within pharmaceutical, biotech, or other regulated global industries.
• Familiarity with enterprise transformation frameworks, Agile delivery models, and data-driven performance measurement.
• Experience leading cross-functional initiatives that span business, data, and technology domains.
• Demonstrated expertise ingovernance operations, partner engagement, and executive reporting.
• Proficiency in financial oversight, vendor management, and forecasting.
• Strong analytical mentality with the ability to design and interpret performance dashboards.
• Exceptional communication, facilitation, and influence skills across matrixed environments.
• Successfully collaborate with global capability centers or offshore delivery teams.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.