Director, Digital Product Operations

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director, Digital Product Operations

What you will do

Let’s do this. Let’s change the world. In this vital role you will help establish, scale, and continuously improve Amgen’s Digital Product Operating Model (DPOM) across the enterprise. Reporting to the Executive Director, Product Management Hub, this leader will own the operating infrastructure that enables Amgen’s shift from projects to products, including the DPOM playbook, product management standards, enterprise tooling strategy, adoption measurement, and integration of product ways of working into core business, technology, finance, agile, and governance rhythms. This role will translate product management principles into practical, repeatable systems that teams across Amgen can understand and adopt. The Director will be accountable for creating and maintaining the DPOM playbook as a trusted enterprise resource; defining how product practices, decision rights, lifecycle standards, OKRs, roadmaps, portfolio planning, intake, documentation, and measurement work in practice; and embedding these practices into enterprise operating cadences. The role will also lead research and recommendations for digital tools that support DPOM, including tools for roadmapping, OKRs, portfolio planning, intake, product analytics, and documentation. This leader will evaluate options, align stakeholders, present recommendations to leadership, and drive adoption of selected tools across the enterprise.

Responsibilities:

Digital Product Operating Model and Playbook Ownership

• Own, evolve, and maintain Amgen’s DPOM playbook, including standards, lifecycle practices, operating rhythms, governance touchpoints, roles, decision rights, and ways of working.
• Translate enterprise product management principles into clear, practical, and scalable guidance for product teams, product groups, business functions, and enabling organizations.
• Partner with Product Management Hub leadership to continuously refine DPOM based on feedback, adoption patterns, maturity insights, and evolving enterprise needs.
• Create clarity on what good product management looks like, including outcome orientation, customer/user problem definition, roadmap quality, prioritization, OKRs, discovery, and value realization.

Product Operations, Tooling, and Enterprise Enablement

• Lead research, evaluation, and recommendation of enterprise tools that support DPOM, including roadmapping, OKRs, portfolio planning, intake, product analytics, and product documentation.
• Partner with business, technology, finance, governance, Agile Enablement, Enterprise Architecture, Change Management, and other enabling teams to define tooling needs and adoption requirements.
• Present clear, evidence-based tooling recommendations to senior leadership and lead adoption of selected tools across the enterprise.
• Establish scalable operating mechanisms that improve transparency, prioritization, planning, and value tracking.

DPOM Adoption, Measurement, and Maturity

• Own the enterprise measurement system for DPOM adoption, maturity, and effectiveness.
• Define metrics, maturity indicators, and reporting mechanisms that show how product ways of working are being adopted across product groups and business functions.
• Track adoption patterns, maturity progression, risks, and capability gaps, and provide data-informed recommendations to Product Management Hub leadership and senior stakeholders.
• Use measurement to drive continuous improvement of DPOM standards, playbooks, tooling, training, and adoption approaches.

Enterprise Operating Rhythm and Stakeholder Partnership

• Partner closely with Agile Enablement, Finance, Governance, Enterprise Architecture, Change Management, business functions, and digital product leadership to embed DPOM into enterprise-wide cadences.
• Act as a connective leader across product, technology, business, finance, and governance stakeholders.
• Influence leaders across functions to adopt outcome-driven, product-centric ways of working.
• Lead through influence in a complex enterprise environment, balancing consistency of standards with pragmatic adoption in different business contexts.

Leadership and Change Enablement

• Serve as a product operations thought leader and advocate for Amgen’s shift from projects to products.
• Eventually lead and develop a small Product Operations team, expected to include 1–2 direct reports over time.
• Model strong prioritization, structured problem-solving, judgment, and enterprise-minded decision-making.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Product Operations leader we seek is an enterprise-minded product leader with these qualifications.

Basic Qualifications:

• Doctorate degree and 4 years of Digital Product Management, Product Operations, or Digital Transformation experience OR
• Master’s degree and 8 years of Digital Product Management, Product Operations, or Digital Transformation experience OR
• Bachelor’s degree and 10 years Digital Product Management, Product Operations, or Digital Transformation experience

In addition to meeting at least one of the above requirements, you must have at least 4 years’ experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources.Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

• 5+ years of progressive experience in product operations, digital product management, enterprise operating model design, product transformation, or related disciplines.
• Experience designing, scaling, or operationalizing product operating models in large, complex organizations.
• Strong understanding of digital product management practices, including product strategy, roadmaps, OKRs, prioritization, discovery, intake, portfolio planning, product analytics, and value realization.
• Experience selecting, implementing, or driving adoption of enterprise tools for roadmapping, OKRs, portfolio management, intake, analytics, or documentation.
• Experience defining adoption, maturity, and effectiveness metrics for enterprise-wide transformation or operating model change.
• Strong cross-functional leadership skills, with the ability to influence senior stakeholders across business, technology, finance, governance, agile, architecture, and change management teams.
• Excellent communication and storytelling skills, including the ability to simplify complex concepts for executive, functional, and delivery team audiences.
• Experience in healthcare, biotechnology, or other regulated industries preferred; candidates from high-tech, digital, consulting, or product-led organizations are also encouraged to apply.
• Familiarity with AI-native product development, generative AI workflows, responsible AI principles, and the evolving role of AI in product management preferred.
• Comfort operating in ambiguity and building new capabilities where standards, processes, and operating rhythms are still being defined.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.