US Rare Disease Medical - Program Manager

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Program Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will play a critical role in planning, executing, and delivering projects on time and within budget. This individual partners with cross-functional teams, proactively manages risks, resolves challenges, and ensures all deliverables meet Amgen’s high standards of quality. This role supports the U.S. Medical Lead(s) in driving and executing product strategy for high-priority Rare Disease assets.

Responsibilities

• Liaise with cross-functional partners to manage US processes, advance alignment, and ensure deliverables are met.

• Support US Rare Disease Medical Lead(s) and US Rare Disease Medical Team(s) in planning and executing product strategy for high-priority rare disease programs.

• Organize and facilitate team meetings with a strong focus on timeliness and efficiency — preparing agendas, recording minutes, ensuring presentations are ready, distributing pre-reads, and managing follow-ups.

• Oversee and track critical team initiatives, including budget management

• Help keep critical projects within budget and timeline; proactively manage risks

• Drive operational excellence and automation by evaluating and integrating emerging technologies (including AI tools such as CoPilot) where appropriate.

• Operate independently and with ambiguity, demonstrating adaptability in dynamic environments and applying continuous-improvement practices.

Competencies & Behaviors

• Thrives in a high-performance culture with agility and accountability in a fast-paced, results-driven environment.

• Strong project management capabilities including planning, priority setting, multi-tasking, and consistent on-time delivery.

• Exceptional time management, decision-making, and organizational skills, with the ability to efficiently locate and synthesize key information.

• Strategic thinker who anticipates challenges, identifies opportunities, and proposes pragmatic, effective solutions.

• Analytical and detail-oriented, capable of applying research insights to develop and implement logical, data-driven action plans.

• Makes well-supported recommendations to advance team and organizational objectives.

• Demonstrates a growth mindset with a passion for continuous improvement, adaptability, and proactive learning.

• Embraces feedback constructively to drive improvement and performance enhancement.

• Operates independently and confidently in ambiguous or evolving situations

• Collaborative and professional communicator with strong interpersonal skills — able to motivate, influence, and enable cross-functional collaboration across all levels.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a manager with these qualifications.

Basic Qualifications:

• Doctorate degree OR

• Master’s degree & 2 years of Project Management experience OR

• Bachelor’s degree & 4 years of Project Management experience OR

• Associates degree & 8 years of Project Management experience OR

• High school diploma / GED & 10 years of Project Management experience

Preferred Qualifications:

• Project Management experience in the biotech industry.

• Rare Disease experience and/or a strong scientific background.

• Experience navigating complex processes and matrixed organizations.

• Excellent communication skills, with the ability to build strong, lasting relationships and collaborate effectively across diverse teams.

• Proven success managing multiple priorities and maintaining quality under pressure.

• Technical fluency and curiosity for emerging technologies, with demonstrated experience integrating AI tools like CoPilot into daily operations.

• Proficiency in SharePoint and/or MS Teams for seamless collaboration.

• Experience working within Medical or alongside Medical teams, with the ability to translate complex information into clear actions.

• Approaches collaboration with enthusiasm, curiosity, and emotional intelligence, fostering trust and alignment across teams.

• Demonstrated success coordinating teams in a matrix environment and aligning cross-functional stakeholders

• Ability to lead comprehensive budget planning and management, including forecasting and proactive risk mitigation.

• Experience working with Amgen systems such as Ariba and SAP, and with Compliance, Legal, and Regulatory partners

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.