Senior Manager Capabilities and Change Management

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Manager Capabilities and Change Management

What you will do

Let’s do this. Let’s change the world.

This role sits at the center of Amgen’s transformation agenda, working directly with RDO leadership to shape how transformation and change are executed across the enterprise.

As a Senior Manager, you will help define and scale the methods, tools, and knowledge systems that enable consistent, high-quality execution of Amgen’s most critical initiatives. Rather than advising from the sidelines, you will work hands-on to build, refine, and embed the capabilities that determine whether transformation efforts succeed or stall.

You will operate across a broad and evolving portfolio of initiatives, partnering with senior stakeholders to bring structure to ambiguity, align ways of working, and ensure modern approaches to change are adopted in practice—not just defined.

This is a high-visibility role with direct exposure to enterprise priorities, requiring a balance of structured problem solving, change leadership, and practical execution.

• Define and operationalize modern change and transformation methods, playbooks, templates, and tools, ensuring they are practical, fit-for-purpose, and applied in real work.
• Clarify how and when tools should be used, reducing duplication, fragmentation, and tool sprawl to create a coherent operating model.
• Partner with transformation teams to embed methods into day-to-day ways of working, reinforcing consistent application across initiatives.
• Establish and scale a knowledge management capability, including content ownership, curation, and access, and define how knowledge is captured, structured, and reused across teams.
• Build and evolve mechanisms (e.g., forums, content hubs) that enable practical knowledge sharing, integrating them into how teams operate.
• Promote consistent application of modern, outcome-oriented change management approaches, supporting practitioners through guidance, tools, and targeted coaching.
• Identify where adoption breaks down and implement focused interventions to improve uptake and effectiveness.
• Drive effective use of key platforms (e.g., digital change platforms, toolkit site, AI-enabled tools) by ensuring they are aligned to practitioner needs and integrated into workflows.
• Use data and feedback to continuously improve usability, relevance, and impact.
• Connect work across capability, methods, and technology, clarifying ownership and ensuring a cohesive approach across the transformation ecosystem.
• Facilitate alignment with senior stakeholders and help establish clear direction and scalable ways of working.
• Build strong relationships across RDO, SLT, and cross-functional teams, influencing without authority to drive alignment and progress.
• Demonstrate ownership, accountability, and a strong bias toward delivering tangible outcomes.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of business performance experience

Or

Master’s degree and 7 years of business performance experience

Or

Bachelor’s degree and 9 years of business performance experience

Preferred Qualifications:

• Experience in top-tier consulting, transformation, or operational roles with clear ownership of delivery
• Demonstrated ability to move from strategy to execution, not just analysis
• Strong track record of operating in ambiguous, fast-moving environments and driving work forward
• Experience leading or supporting change management and adoption at scale
• Ability to identify gaps and inefficiencies and implement practical, high-impact solutions
• Experience working across business, technology, and functional teams
• Strong communication and stakeholder management skills, with ability to influence senior leaders
• Comfort operating with partial ownership in a matrixed environment
• Exposure to digital platforms, analytics, or AI-enabled tools in a business context
• High ownership mindset with a consistent track record of driving results through others

Why this role is different:

• From advising to owning: You will directly shape how transformation is executed—not just recommend what should be done
• Enterprise exposure: Work at the center of Amgen’s most critical initiatives with visibility to senior leadership
• Build something durable: Create scalable methods, tools, and capabilities that outlast individual programs
• Broaden impact: Influence change across functions, geographies, and business units

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.