Enterprise Programs Director

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

Let’s do this. Let’s change the world. We are seeking a seasoned Enterprise Programs Director to lead the successful execution of complex, multi-year strategic programs that drive transformation across Amgen’s global enterprise. This individual will serve as a central figure in ensuring the on-time delivery of large-scale, cross-functional initiatives, managing transformation budgets, and delivering consolidated program dashboards to executive stakeholders. The ideal candidate brings extensive experience running large, transformational programs that involve solving complex problems, managing intricate stakeholder relationships, and navigating highly complex program interactions.

Responsible for:

• Serve as the principal leader for enterprise-scale programs, overseeing multiple interdependent projects across business and technology domains.
• Ensure on-time delivery of milestones by proactively managing risks, issues, and dependencies across global workstreams.
• Drive strong program governance and maintain rigorous program discipline using structured methodologies.
• Solve highly complex problems by bringing structured thinking, creative approaches, and cross-functional collaboration to challenges that span the enterprise.
• Manage complex stakeholder relationships across senior executives, global functions, regional operations, and external partners to ensure alignment and successful outcomes.
• Navigate highly complex interactions within and across programs to ensure integration, prioritization, and optimization of enterprise resources.
• Lead cross-functional programs that integrate technology and business functions, ensuring that solutions meet both technical and strategic business needs.
• Design and maintain consolidated dashboards that track key KPIs, timelines, and resource utilization.
• Provide accurate, real-time reporting to executive leadership and steering committees, synthesizing complex data into actionable insights.
• Manage program budgets across multiple cost centers and funding sources, including capital and operational expenditures.
• Partner with Finance, Procurement, and functional leaders to ensure accurate forecasting, tracking, and compliance with global policies.
• Facilitate cross-functional collaboration, aligning business priorities with program outcomes and enterprise value delivery.
• Present program updates to senior executives and global governance forums, ensuring transparency and alignment.
• Lead and mentor a high-performing team of program and project managers.
• Oversee third-party vendors and consultants, ensuring commitments are delivered on scope, quality, and time.
• Foster a culture of accountability, transparency, and continuous improvement.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

• Doctorate degree and 4 years of Scientific and/or Operations and/or Business experience Or
• Master’s degree and 7 years of Scientific and/or Operations and/or Business experience Or
• Bachelor’s degree and 9 years of Scientific and/or Operations and/or Business experience

Preferred Qualifications:

• 10+ years’ experience in Biotechnology / Pharmaceutical or related industries, with a strong focus on enterprise program and portfolio management.
• Proven track record of leading large-scale, transformational programs involving complex problem-solving, multi-stakeholder management, and highly interdependent program environments.
• Extensive experience managing cross-functional programs, including technology-focused programs that directly impact business functions.
• Strong expertise in program governance, risk management, and stakeholder alignment.
• Excellent oral and written communication skills, including the ability to prepare executive-level presentations and influence senior leadership.
• Strong technical and analytical skills using digital tools to support decision-making and program execution.
• Demonstrated ability to bring structure to complex problems, pragmatically scope solutions, and lead execution to completion.
• Strong leadership and people management skills, with a demonstrated ability to inspire and influence across different levels and functions.
• Knowledge of drug development, operations, or regulated environments is highly desirable.
• Independent, motivated, and collaborative professional with experience in a matrixed environment.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. 

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors, including but not limited to, relevant skills, experience, and qualifications. 

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: 

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. 

• A discretionary annual bonus program. 

• Stock-based long-term incentives. 

• Award-winning time-off plans and bi-annual company-wide shutdowns. 

• Flexible work models, including remote work arrangements, where possible. 

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.