Senior Associate – Oligonucleotides

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Associate

What you will do

Let’s do this. Let’s change the world. In this vital role you will be part of the Genetic Medicines group with responsibilities including contribution to the design, synthesis, and purification of novel compounds for discovery and delivery of oligonucleotides, mechanistic understanding and application of RNA technologies, and potential clinical drug development.

The candidate will use their experimental background in oligonucleotide chemistry and biochemistry from hands-on experience in synthetic organic chemistry, oligonucleotide synthesis, and chemical and biophysical characterizations and demonstrate a consistent, analytical approach to problem solving and experimental design

• Synthesis, purification, and analysis of oligonucleotides in an automated laboratory environment

• Conjugation of lipids, carbohydrates and other building blocks to be used for intracellular RNA delivery

• Prepare clearly articulated experimental reports and data presentations

• Analyze, interpret, and coordinate data to present in internal meetings

• Additional responsibilities may include advising colleagues in areas of expertise; providing scientific results that support the generation of publications, patents, or regulatory submissions; participating in national scientific meetings.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

Basic Qualifications:

• Master’s degree

Or

• Bachelor’s degree and 2+ years of scientific experience

Preferred Qualifications:

• Master’s degree in Chemistry

• 2+ years of post-degree laboratory research experience with emphasis in oligonucleotide chemistry in an industrial or academic setting.

• Strong experience in oligonucleotide synthesis in a high-throughput automated laboratory environment; experience in chemistry of oligonucleotides, nucleic acid modifications, and delivery of oligonucleotide therapeutics

• Solid laboratory skills in synthesis, purification, and characterization of small molecules and oligomers, familiarity with state-of-the-art analytical techniques such as LC, MS, NMR, and the ability to analyze, interpret, and present data.

• Flexibility to be able to apply knowledge to new areas of study, thrive in a team environment, and possess good communication skills

• Demonstration of good lab practices with attention to safety

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.