Health Impact Framework Implementation, Senior Manager

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Health Impact Framework Implementation Senior Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will play a critical role in operationalizing Amgen’s Health Impact Framework, ensuring that inclusive design, patient insights, and measurable health-impact principles are integrated into decisions across the enterprise.

Reporting to the Executive Director, Health Impact, you will be the primary driver of framework implementation, working closely with teams across R&D, Development, Clinical, Regulatory, Commercial, and Access. This role is ideal for a strategic operator who excels at translating vision into action, bringing structure to ambiguity, and coordinating complex, cross-functional workstreams.

Key Responsibilities

• Implement and Operationalize the Health Impact Framework
  • Lead day-to-day execution and continuous refinement of Amgen’s Health Impact Framework across the asset lifecycle.
  • Develop operational guidance, playbooks, and tools that enable functions to apply the Framework consistently and effectively.
  • Coordinate with analytics, digital, and data-science teams to build measurement dashboards and define KPIs that track progress and outcomes.
  • Support integration of framework principles into asset plans, clinical development strategies, access roadmaps, and lifecycle management.
• Cross-Functional Alignment & Delivery
  • Partner with Clinical Development, RISE, ATH, Regulatory, Medical, Commercial, and Policy teams to embed inclusive-design and patient-impact considerations in strategic and operational plans.
  • Manage processes that surface insights, gaps, and opportunities to improve equitable outcomes across priority populations.
  • Facilitate cross-functional governance meetings; prepare materials, synthesize recommendations, and track action plans.
• Program & Change Management
  • Develop and execute a change-management plan to drive adoption of health-impact thinking across the enterprise.
  • Create scalable processes, templates, and standard operating approaches to ensure sustainability.
  • Identify barriers to implementation and develop mitigation strategies to maintain momentum.
• Stakeholder & External Engagement Support
  • Support the Executive Director in preparing for leadership briefings, external engagements, and communications related to health impact.
  • Coordinate with academic, community, and policy partners to incorporate emerging insights and best practices into Amgen’s approach.
• Team Leadership & Culture
  • Provide project leadership to cross-functional contributors and mentoring to junior IGHI team members.
  • Foster a culture of collaboration, innovation, and patient-centered problem-solving.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.

Basic Qualifications:

• Doctorate degree and 2 years of relevant experience OR
• Master’s degree and 6 years of relative experience OR
• Bachelor’s degree and 8 years of relative experience OR
• Associate’s degree and 10 years of relative experience
• OR High school diploma / GED and 12 years of relative experience

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources.  Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

• Experience implementing enterprise frameworks, strategic initiatives, or cross-functional programs in healthcare, life sciences, clinical research, patient access, public health, or related domains.
• Strong understanding of health equity, disparities, social determinants, or patient-access dynamics.
• Familiarity with clinical trials, regulatory considerations, and inclusive research practices.
• Demonstrated ability to manage complex stakeholder environments and influence without authority.
• Experience with data analytics, digital tools, or AI-driven insights to guide decision-making.
• Proven program-management skills with a track record of delivering operational outcomes in matrixed organizations.
• Excellent communication and synthesis skills—able to translate complex concepts into actionable guidance.
• High learning agility, resilience, and comfort operating in fast-evolving strategic spaces.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.