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Senior Scientist

US - California - South San Francisco Apply Now
JOB ID: R-210281 LOCATION: US - California - South San Francisco WORK LOCATION TYPE: On Site DATE POSTED: Mar. 27, 2025 CATEGORY: Scientific SALARY RANGE: 130,278.00 USD - 151,932.00 USD

Senior Scientist, Inflammation

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Scientist, Inflammation

What you will do

Let’s do this. Let’s change the world. The Department of Inflammation at AMGEN Inc. is currently seeking a dedicated senior scientist to contribute to our research efforts in developing new treatments for inflammatory and autoimmune diseases. This role requires a commitment to developing a deep understanding of the pathogenic mechanisms that underlie inflammatory diseases. In this vital role, you will be driving discovery efforts to identify how Amgen’s innovative modalities can improve the lives of patients who suffer from inflammatory and autoimmune diseases and related co-morbidities.

  • Identify new therapeutic targets, execute on existing targets and conduct preclinical validation. The candidate should remain informed about scientific advancements in inflammatory diseases, drug screening methods, and the evolving landscape of unmet needs in patients with these conditions.

  • Independently design, perform, and analyze laboratory experiments encompassing in vitro, ex vivo, in silico, and in vivo methodologies. This includes troubleshooting, optimizing assays, collecting data, interpreting results, and conducting biostatistical analyses.

  • Summarize and synthesize data across experiments and present findings across all levels at AMGEN, at scientific conferences and by publishing scientific papers in peer-reviewed journals.

  • Participate as a key intellectual and technical contributor in cross-functional drug development teams.

  • Perform effectively in a team-based or collaborative environment as part of a highly integrated team. Exhibit excellent organizational, verbal, and written communication skills, produce reliable and reproducible results, multitask efficiently, and coordinate multiple projects confidently.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional we seek is a [type of person] with these qualifications.

Basic Qualifications:

  • Doctorate degree

Or

  • Master’s degree and 3+ years of relevant experience

Or

  • Bachelor’s degree and 5+ years of relevant experience

Preferred Qualifications:

  • Research Experience: PhD in biology, immunology or a related discipline with over 5 years of experience in immunology-related research in industry or academic settings.

  • Scientific Contributions: Demonstrated track record of independent scientific contributions in immunology, as evidenced by publications in high-impact journals.

  • Technical Skills: Experience with small and large molecule drug discovery, including designing and implementing strategies to elucidate the mechanism of action of targeted therapies. Proficiency in immuno-pharmacological techniques such as in vitro and ex-vivo immune cell-based assays, ELISA, MSD, and flow cytometry-based immune cell profiling is highly desirable. Experience with primary cell culture and functional screening, single-cell RNA sequencing (scRNA-Seq), CRISPR/Cas9, and omics data analysis experience a plus.

  • Collaborative Skills: Proven ability to work effectively in team environments with strong documentation and laboratory management skills. Excellent written and oral communication skills to clearly articulate scientific proposals and results, lead discussions, and make presentations in multidisciplinary meetings.

  • Innovative Thinking: A creative and innovative approach to identify and validate novel targets and therapeutic approaches. This includes staying abreast of current trends, literature, and new developments in pre-clinical and clinical development.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans

  • Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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