Manager Engineering - Drug Substance Process Engineering

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Manager Engineering - Drug Substance Process Engineering

Live

What you will do

Let’s do this. Let’s change the world! In this vital role will lead Engineering Process Support Organization at the AML7 Drug Substance Operations. Responsible for supervising, hiring, and developing staff. Ensuring operations uptime and activities are completed on time while maintaining safety, quality, and financial objectives.

Specific responsibilities include but are not limited to:

• Lead a team of engineers supporting 24/7 manufacturing operations, focused on equipment reliability and system uptime.
• Plan, prioritize, and coordinate day-to-day engineering support and technical troubleshooting across manufacturing areas.
• Support the execution of preventive, corrective, and predictive maintenance activities in compliance with safety and regulatory requirements.
• Provide technical direction for resolving process and equipment issues, including leading root cause investigations and implementing preventive measures.
• Track and analyze equipment performance metrics (KPIs), identifying opportunities for improvement.
• Lead or support capital and expense projects related to equipment upgrades, process enhancements, and system improvements.
• Ensure engineering documentation is accurate and updated, including change controls, validation protocols, and standard operating procedures.
• Collaborate cross-functionally to support investigations and regulatory inspections.
• Promote a safe work environment, ensuring adherence to EHSS standards and supporting safety initiatives.
• Support staff training, performance evaluation, and development planning in alignment with business needs.
• Participate in the planning and coordination of plant downtime activities, ensuring proper execution of maintenance and engineering work.
• Align with site-level engineering standards, and support global benchmarking initiatives when required.
• Provide technical support during New Product Introductions (NPIs) to ensure seamless integration into operations.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients! The Manager Engineering professional we seek is a collaborative leader with these qualifications.

Basic Qualifications:

Doctorate degree in Engineering

Or

Master’s degree in Engineering and 3 years of Engineering and/or Process Manufacturing experience

Or

Bachelor’s degree in Engineering and 5 years of Engineering and/or Process Manufacturing experience

In addition to meeting at least one of the above requirements, you must have previous managerial experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above.

Beyond that, additional preferred qualifications are:

• Experience using PI Vision for data visualization and monitoring.
• Familiarity with SIMCA software for multivariate data analysis is a plus.
• Background in process manufacturing and/or engineering within drug substance production.
• Proven ability to lead technical teams, with strong troubleshooting and problem-solving skills.
• Proficiency in English and Spanish, with excellent verbal and written communication skills.
• Experience with Lean Six Sigma methodologies and a continuous improvement mindset.
• Flexibility to support a 7/24, non-standard shift operations.
• Strong financial acumen, including experience in budget planning and management.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and an annual site shutdown
• Flexible work models, including remote work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.