Senior Engineer Manager - Upstream
Senior Engineer Manager - Upstream
US - North Carolina - Holly Springs Apply NowJoin Amgen’s Mission of Serving Patients
At Amgen, if you feel likeyou’repart of something bigger,it’sbecause you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980,we’vehelped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team,you’llhelp make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities thatliewithin them,you’llthrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the AmgenFleXBatch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. TheFleXBatch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
SeniorEngineerManager - Upstream
Live
What you will do
Let’sdo this.Let’schange the world. In this vital role you willbe responsible forthe department capital portfolio andproject management of small capital projects at the drug substance facility inANC.
Reporting to the Director of Engineering, the Sr Manager will provide technical leadership to a team of manufacturing support engineers supporting commercial production operations with emphasis on Drug Substance bioprocessing equipment.
Establish clear expectations and priorities to staff. Encourage a culture of continuous improvement, partnership, and knowledge sharing. Provide development opportunities, feedback, and actively listen to staff.
Cultivate a culture of safety ensuring the well-being of all staff members and drive efforts to reduce safety risks.
Provide technical support to troubleshoot, identify and resolve process and system issues as needed.
Be knowledgeable about compliance and regulatory aspects for equipment validation, operation and maintenance.
Effectively collaborate with key customers and support groups (e.g. Manufacturing, Quality, Process Development, Maintenance, network partners).
Ensure all tasks and projects are accomplished in a safe manner.
Employ Business Analytics to assess performance andidentifyimprovement opportunities
Lead Sustainability Program Management of Multi-faceted, Cross-functional,Network Initiative
Collaborates with leadership to set strategy and businessobjectives.
Foster andmaintainrelationships with key stakeholders.
Establish balanced scorecard of strategic and operational key performance indicators(KPI) in line with industry best practices tomonitor, trend and analyzeequipmentperformance,sustainabilityand reliability programs.
Ensure action plans areestablishedto address performance gaps or opportunities.
Communicate gaps andestablishthe proper escalation process to the stakeholders
Identifyopportunities tooptimizeorganizational efficiency.
Leads engineering and contractor evaluation and selection process
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional weseekis a [type of person] with these qualifications.
Basic Qualifications:
High school diploma / GED and 12 years of Engineering and/or ProjectManagement experience OR
Associate’s degree and 10 years of Engineering and/or Project Management experience OR
Bachelor’s degree and 8 years of Engineering and/or Project Management experience OR
Master’s degree and 6 years of Engineering and/or Project Management experience OR
Doctorate degree and 2 years of Engineering and/or Project Management experience
Additionally: In addition to meeting at least one of the above requirements, you must have a minimum of 2years experiencedirectly managing people and/or leadership experience leading teams, projects, programs, or directing the allocationorresources. Your managerial experience may run concurrently with the required technical experience referenced above
Preferred Qualifications:
Bachelor’s degree in chemical engineering or related technical field
5+ years’ experience in engineering in a manufacturing support environment with 3+ years’ experience in the Pharmaceutical or Biotechnology industries
Demonstrated people management/leadership experience
Experience with Mammalian Cell Culture, Protein Purification, Clean Utilities, CIP, SIP and Production Services. Upstream unit operation experience such as bioreactor or harvest equipment
Familiarity designing, troubleshooting, and operating equipment used in cell culture manufacturing including disposable technologies
Experience with Tech Transfer, Process Design, and Commissioning & Qualification
Experience with validation and change control methodology
Direct experience with regulated environments (i.e., cGMP, OSHA, EPA) including detailed understanding of cGMPs
Excellent written and verbal communication skills
Demonstrated interpersonal and facilitation skills and ability to work in a collaborative team-based environment
Ability to apply analytical skills to evaluate and interpret complex problems using multiple sources of information
Demonstrated ability to lead and influence cross-functional teams and embrace a team-based culture
Familiarity with designing and operating equipment used in biopharmaceutical manufacturing
Demonstrated experience in applying Operational Excellence and Lean Manufacturing
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Apply nowfor a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
#AmgenNorthCarolina
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation toparticipatein the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
