Scientist - Target Discovery Platforms - Biology

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist - Target Discovery Platforms - Biology

What you will do

In this vital role, you will join the Predictive Biology team at Amgen British Columbia, driving the advancement of our target discovery platform through state-of-the-art stem cell and organoid biology. We are seeking a scientist with deep expertise in induced pluripotent stem cells (iPSC) and organoid systems who thrives in a collaborative, fast-paced environment and is passionate about translating complex biology into scalable discovery models.

As a key member of the laboratory team, you will:

• Apply your understanding of iPSC differentiation and organoid culture to ensure biological fidelity and reproducibility of complex models running on automated platforms.
• Partner with downstream teams to validate and benchmark these models, linking cellular phenotypes to target biology.
• Refine and expand differentiation protocols to incorporate new tissue types and improve physiological relevance.
• Bring scientific rigor and curiosity to data interpretation, model troubleshooting, and continuous improvement.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

Basic Qualifications:

• BS/MS Degree

Preferred Qualifications:

• Master’s degree (or equivalent experience) in Cell or Molecular Biology, Developmental Biology, Pharmacology, or a related discipline, with 3+ years of laboratory experience in academic, biotechnology, or pharmaceutical research.
• Extensive hands-on experience with human iPSCs, including differentiation into relevant lineages and establishment of 3D organoid models.
• Experience working with primary human and patient-derived samples, including tumor organoids, with ability to tailor culture conditions to maintain viability and phenotype.
• Proficiency in adapting iPSC and organoid systems for integration with automated culture platforms, ensuring biological fidelity, stability, and reproducibility under automated operation.
• Demonstrated ability to develop, optimize, and troubleshoot complex cell-based assays, including high-content imaging, immunofluorescence, or luminescence-based functional readouts.
• Strong understanding of cellular physiology and functional biology, with the ability to interpret culture performance and phenotype across diverse disease contexts.
• Excellent communication and collaboration skills, with demonstrated success working across functional teams
• Scientific curiosity, rigor, and problem-solving mindset, with enthusiasm for advancing discovery through innovative, automation-enabled biological model systems.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth. Click HERE for more details.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team.

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As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.