Enterprise Programs - Senior Program Manager

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Enterprise Programs - Senior Program Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead strategic, business-driven technology initiatives that deliver measurable outcomes and business value. This role is ideal for a seasoned program leader with a strong understanding of both business processes and enterprise technology. You will oversee a portfolio of transformational initiatives aimed at enabling innovation, improving operational efficiency, and advancing data-driven decision making.

You will work in a global, matrixed environment and collaborate closely with cross-functional partners across business units, technology functions and external partners. A key focus will be on aligning technology delivery with business priorities, ensuring every program contributes to tangible, strategic outcomes. You’ll need a proven ability to translate vision into execution, manage change, and influence cross-functional stakeholders at all levels of the organization.

Key Responsibilities:

• Lead delivery of complex programs that align to enterprise goals and deliver measurable value!

• Drive transformational programs to deliver on business priorities

• Work closely with business stakeholders to define outcomes, ensure solutions are implemented as planned and drive adoption

• Translate business needs into executable program plans, including scope, timelines, resource planning, and budget oversight

• Partner with cross-functional teams including data & analytics, enterprise applications, and digital product teams to deliver outcomes

• Manage program governance, steering committees, and status reporting for senior partners

• Drive structured methodologies such as Agile, SAFe, or hybrid approaches to improve delivery efficiency and responsiveness

• Track program KPIs, ROI, and performance metrics aligned to business success criteria

• Coordinate organizational change, business readiness, and stakeholder engagement activities across functions and geographies

• Build trust and alignment across technology teams and business leaders to sustain long-term strategic partnerships

• Apply continuous improvement practices to program execution and delivery frameworks.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek will have these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Scientific and/or IT Operations and/or Business experience

Or

Master’s degree and 4 years of Scientific and/or IT Operations and/or Business experience

Or

Bachelor’s degree and 6 years of Scientific and/or IT Operations and/or Business experience

Or

Associate’s degree and 10 years of Scientific and/or IT Operations and/or Business experience

Or

High school diploma / GED and 12 years of Scientific and/or IT Operations and/or Business experience

Preferred Qualifications:

• 6–10 years of experience delivering business technology solutions and programs in a matrixed, global organization

• Demonstrated success in aligning technology execution with business strategy to achieve measurable outcomes

• Experience leading transformational programs or M&As

• Experience leading programs involving business process optimization, digital product rollouts, enterprise applications, or analytics platforms

• Proficiency with program and portfolio management tools (e.g., Smartsheet, JIRA, ServiceNow, Confluence) and executive reporting dashboards.

• Strong stakeholder engagement, communication, and change leadership skills across business and technical audiences

• Ability to manage vendor relationships and third-party service providers in a co-delivery model.

• Familiarity with data privacy, GxP, and regulatory compliance frameworks in a life sciences context

• PMP, SAFe, Agile, or Lean certification preferred!

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.