Senior Associate (In Vivo Pharmacokinetics and Drug Metabolism )

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Associate

What you will do

Let’s do this. Let’s change the world.

We are seeking a highly motivated, detail-oriented, and collaborative Senior Associate to support In Vivo Pharmacokinetics and Drug Metabolism – Bioanalytical (PKDM-BA) research activities within a dynamic drug discovery environment. This role is designed to work closely with and support senior scientists and experienced research team members in advancing novel therapeutic candidates across a diverse multimodality portfolio. The successful candidate will contribute to preclinical in vivo PKDM studies focused specifically on mouse and rat models while developing technical expertise within a highly collaborative research setting.

Key Responsibilities:

• Support senior team members in the execution of preclinical in vivo PKDM-BA studies using mouse and rat models.
• Assist with routine handling, restraint, husbandry support, and dosing of mice and rats through multiple administration routes including intravenous (IV), oral gavage (PO), subcutaneous (SC), and intraperitoneal (IP).
• Perform biological sample collection from rodents including blood, plasma, serum, urine, feces, and tissue specimens under the guidance of experienced scientists and study leads.
• Conduct clinical observations, monitor rodent health and welfare, and accurately document findings in accordance with study protocols and institutional guidelines.
• Support rodent necropsy procedures, tissue collection and processing, and basic surgical manipulations as directed by senior staff.
• Prepare study materials, dosing formulations, laboratory supplies, and associated documentation to facilitate efficient study execution.
• Maintain accurate, organized, and compliant experimental records and laboratory documentation.
• Assist with laboratory organization, equipment readiness, and inventory management of research consumables and animal study supplies.
• Adhere to institutional animal care and use guidelines, SOPs, and laboratory safety procedures.
• Collaborate effectively with scientists, veterinarians, and laboratory staff to support research timelines and study objectives.
• Participate in team meetings, technical training, and discussions to build technical knowledge and professional development.
• Contribute to continuous improvement initiatives, workflow optimization, and operational excellence activities within the vivarium and laboratory environment.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The successful candidate will partner closely with senior team members, scientists, and cross-functional research teams to assist in the execution of rodent studies, biological specimen collection, dosing procedures, study preparation, and experimental documentation. This position offers valuable hands-on experience supporting PKDM, ADME, and translational research activities critical to early drug development.

Basic Qualifications:

• Master’s degree

OR

• Bachelor’s degree with a minimum of 2 years of rodent laboratory animal research experience;

OR

• Associate’s degree with a minimum of 4 years of rodent laboratory animal research experience
• High school diploma / GED with a minimum of 6 years of rodent laboratory animal research experience.

Preferred Qualifications:

• Undergraduate degree in Biology, Chemistry, Animal Science, Pharmacology, or related life science discipline.
• Hands-on experience working with mice and rats in academic, biotechnology, or pharmaceutical research environments.
• Experience supporting senior researchers in pharmacokinetic (PK), ADME, or bioanalytical studies in rodent models preferred.
• Familiarity with rodent handling, restraint, dosing techniques, blood collection, and sample processing procedures.
• Basic understanding of pharmacokinetics and the role of in vivo PK studies in advancing therapeutic candidates through preclinical drug development.
• Strong organizational, analytical, written, and verbal communication skills.
• Demonstrated ability to work collaboratively in a team-oriented research environment while continuing to build independent technical skills.
• Ability to manage multiple priorities in a fast-paced research setting with guidance from senior team members.
• Willingness to learn advanced rodent surgical support techniques and specialized in vivo research procedures.
• Proficient in Microsoft Office Suite, including Word, Excel, PowerPoint, and Outlook.
• AALAS and/or ASR certification is considered a plus.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

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Application deadline

External/Internal postings:

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Internal only posting (or Pre-ID candidate):

Amgen anticipates accepting applications until 1-2 weeks before the posting; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.