Organic and Conjugation Chemist

Senior Associate – Organic and Conjugation Chemist

Live

This could be your everyday

Let’s do this. Let’s change the world.

The Hybrid Modality Group at Amgen is seeking a highly motivated scientist in the field of Antibody Drug Conjugates (ADC) to join us in the state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CA. The qualified candidate will work at the interface of synthetic chemistry, biochemistry, and chemical biology, and apply their chemical synthesis skills in developing new antibody drug conjugates to support the advancement of drug discovery programs

Responsibilities include:

• Perform multistep organic synthesis of linker-payload reagents under supervision
• Purify and characterize small molecules using techniques such as flash chromatography, HPLC, LC/MS, and NMR.
• Learn and perform bioconjugation of antibodies, peptides, and small molecule payloads and characterize conjugates using analytical techniques, such as HPLC, LC-MS, and SEC
• Document experimental plans and procedures in electronic lab notebooks while following appropriate SOPs.
• Generate, analyze and summarize scientific data and provide regular updates on project results.
• Operate and maintain standard lab equipment

Win

Here’s what it takes to Win

We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

Basic qualifications

• Master's Degree

Or

• Bachelor's Degree and 2+ years of relevant experience

OR

• Associate’s degree and 4 years of relevant experience

OR

• High school diploma / GED and 6 years of relevant experience

Preferred qualifications

• Experienced in organic synthesis including executing and optimizing chemical reactions
• Basic understanding of purification and analytical methods
• Eagerness to learn chemical conjugation and characterization of ADC
• Demonstration of good lab practices, with particular attention to safety
• Strong written and verbal communication skills

• Ability to work comfortably within a dynamic team of scientists and engineers with diverse technical and cultural backgrounds

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

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Application deadline

External/Internal postings:

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Internal only posting (or Pre-ID candidate):

Amgen anticipates accepting applications until 1-2 weeks before the posting; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.