Scientist - LC-MS Specialist/Analytical Chemistry

Amgen is one of the world’s leading independent biotechnology companies. For four decades, Amgen has pioneered biotechnology breakthroughs to bring state-of-the-art medicines from laboratory to the patient. Amgen Research Copenhagen (ARC), through our DNA Encoded Library (DEL) technology, is contributing significantly to Amgen’s many small molecule drug discovery projects from hit discovery all the way to drug candidate selection.

We are currently seeking a candidate to join a team that operates, supports, troubleshoots, and maintains analytical instruments, while providing expert instrument guidance to users running samples. In addition, the candidate will support the effective use of various LC–MS software packages.  

If you are passionate, analytical, resourceful, practical, goal-oriented, open-minded, conscientious, willing to go the extra mile, enjoy working in the lab in a dynamic environment, and have a desire to contribute to groundbreaking scientific research within a new field of drug discovery, we may have a position for you. 

As a member of the Analytics team, you will help us setup and operate LC-MS systems and various automated sample preparation equipment to ensure high-throughput acquisition, analysis and purification of small molecule including oligo conjugates to deliver high-quality data, take part in method development and implementation of new analytic instruments. The position will primarily involve maintenance and setup of LC-MS systems, but also method development and testing of new setups. You will be working cross-functionally with internal groups specializing in DEL-technology, parallel synthesis, medicinal chemistry and biology, and you will participate with your analytical expertise in the process of identifying and purifying various compounds. 

Specifically, tasks will include: 

·       Daily care of ARC analytical and prep LC-MS.  

·       Keeping LC and MS instruments, including CLND detectors, in excellent operational state. 

·       Software support for all LC and MS based software package 

·       Supervision of LC-MS users 

·       Purification of oligo conjugates and other compounds on LC systems 

·       Keeping track of spare parts for all instruments 

We offer a highly rewarding and stimulating environment in a world-class drug discovery organization. The position is based across our two Østerbro offices, 1.3 km apart, about 4 minutes by bike. 

The employee will report to Scientific Associate Director, Michael Godskesen. For further information contact HR Sr Manager, Rachel Allen (Rallen03@Amgen.com)  

Qualifications:

Preferably, the candidate should hold an M.Sc. or B.Sc. degree in a relevant technical or scientific discipline and have at least three years of experience maintaining and operating LC instruments from multiple suppliers. Laboratory technicians with at least ten years of relevant experience and well-documented training may also be considered. 

The ideal candidate will have: 

·       Proficiency in running analytical as well as preparative samples on various LC-MS platforms 

·       In depth understanding of liquid chromatography and Mass Spectrometry 

·       On hands experience working and maintenance of different LC-MS systems 

·       Competence related to manual and automated sample preparation 

·       Proficiency in Agilent ChemStation and MassHunter software 

·       Familiarity with Waters MassLynx software 

·       Knowledge of Shimadzu LabSolutions software 

·       Experience working with third party analytical software ACD Labs, Mnova or similar 

·       A talent for tidiness, data organization etc.   

·       Excellent collaboration and team player skills 

·       Thrives in a fast-changing environment where priorities and location can change throughout the day 

·       Excellent English communication skills 

·       A confident communicator committed to delivering high-quality results 

Application:

Please note that it is required to have permit to live and work in Denmark for application. All applications and contacts are confidential. We want your application as soon as possible, selection starts instantly.

We do not offer a relocation package for this position.