Undergrad Co-op – R&D (Biochemical Characterization and Novel Screening)

Category: College Job
Job ID: R-69420
Employment Type: Full time
Location: Canada – Burnaby
Posted Date: January 10, 2019

Amgen British Columbia specializes in the discovery and development of human therapeutic antibodies. The research center, located in Burnaby, employs approximately 60 people including research scientists and a small support staff. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the promise of biologic therapeutics and has changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives.

The successful co-op student will be part of a biochemical screening team responsible for the characterization of lead monoclonal antibody panels against diverse targets. The core function of the team is to design fit for purpose secondary screens (e.g. affinity, epitope, receptor/ligand) to enable selection of antibody molecules with properties that meet program design goals. The antibody panels are generated through the immunization of Xenomouse™, which is a proprietary transgenic mouse capable of producing fully human antibodies. The accomplished co-op student will assist with development of novel assays to further characterize lead antibody panels, and will be responsible for an individual research project.

Anticipated Achievements:

  • Bio-Layer Interferometry (Octet)
  • Antibody Quantification
  • Characterization of immune response in immunized animals
  • Molecular Biology
  • Construct design
  • PCR, ligation, DNA scale-up
  • Protein antigen characterization
  • Western Analysis
  • Nanodrop
  • Mammalian and B cell primary cell culture
  • Transfections
  • Data analysis, reporting and presentation

Basic Qualifications:

Amgen requires that all individuals applying for an undergraduate internship or an undergraduate co-op assignment at Amgen must meet the following criteria:

18 years or older

Currently enrolled in a full time Bachelor’s degree program from an accredited college or university with a 3.0 minimum GPA or equivalent

Completion of one year of study from an accredited college or university prior to the internship commencing

Enrolled in a full time Bachelor’s program following the potential internship or co-op assignment with an accredited college or university

Must not be employed at the time the internship starts

Preferred Qualifications:

Degree Concentration(s): Immunology, Chemistry, Molecular Biology, Biochemistry, Biology/Microbiology, Life Sciences, or related discipline

Able to work for two consecutive four month terms with continued employment for the second term dependent on a positive performance review at the end of the first term

High attention to detail, able to comply with written procedures and having excellent record keeping skills

Strong written and oral communications skills

Experienced with Excel, Word and PowerPoint

Strong knowledge of protein biochemistry

Prior co-op experience

All candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment.

Only candidates who apply via http://careers.amgen.com will be considered. We request that all applicants include a cover letter with their resume when they apply. Applicants without a cover letter may not be considered for the position. Please search the database via career category – College Job, keyword 69420.

Amgen retains the right to add or change the duties of the position at any time. As an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace.

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